Mironova V

Date of Birth: 05.03.1983

Work Address: Institute of Cytology and Genetics, Novosibirsk, 630090, Russia (http://www.bionet.nsc.ru/)

Telephone: +7 (383) 363-4922*3408

Fax: +73833331278

Languages: Russian and English.

Education:

2010: PhD in biology (mathematical biology and bioinformatics), Institute of Cytology and Genetics, Novosibirsk, Russia.

Title: “Computational analysis of auxin-regulated mechanisms of root development in plants”
Institute of Cytology and Genetics, Novosibirsk, Russia

Advisor: Dr. Vitaly A. Likhoshvai

2005: M. Sc.in Biology (Informational biology minor), Novosibirsk State University, Novosibirsk, Russia Graduated with Honors (summa cum laude).

Title: “The shoot apical meristem development in Arabidopsis thaliana: genenetwork reconstruction, databasing and modeling”

Advisor: Dr. Nikolai A. Kolchanov and Nadya A. Omelyanchuk

Experience:

2008- till present –staff scientist, Department of systems biology, Institute of Cytology and Genetics, Novosibirsk, Russia
2008- till present – curator of PhD students in Department of systems biology.
June 2010 – vice-chairman of the organizing committee on BGRS\SB-2010 conference.
2007 – Analyst, Center of Financial Technology, Novosibirsk, Russia. Databasing.
2008-2003 Laboratory Assistant, Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Novosibirsk, Russia.

Skills:

Windows, MS Office (Word, Excel, Access, PowerPoint), Adobe (Acrobat, Photoshop), Corel Draw, Mathematica. Basic knowledge of Java, C++ and Pascal. XML, HTML, CSS. Tools and technologies for Databasing, Systems biology, Mathematical modeling.

Research Interests:

Systems biology, mathematical modeling of plant growth and development;

Pattern formation in root apical meristems, auxin transport and signalling.

Participation in Conferences and Workshops:

2011:

V.V. Mironova Scientific workshop “Molecular, cellular and tissue mechanisms of plant growth and development” Siberian Federal University, Krasnoyarsk, Febr. 7-8, 2011.

2010:

V.V. Mironova, E.S. Novoselova, N.A. Omelyanchuk, V.A. Likhoshvai. The mathematical model for investigation of auxin-regulated root patterning in wild type and under treatments. The joint Russian-French seminar “Genomics, Bioinformatics and life science modeling”. 2010. Novosibirsk.
V.V. Mironova, N.A. Omelyanchuk, D.Yu. Oschepkov, V.G. Levitsky PREDICTION FOR AtARF FAMILY TRANSCRIPTION FACTORS, MEDIATING PRIMARY RESPONSE TO AUXIN. In proceedings of the Plant Genetics, Genomics and Biotechnology Conference. 2010. Novosibirsk. P. 46.
Mironova V.V., N.A. Omelyanchuk, E.S. Novoselova, V.A. Likhoshvai. In silico analysis of auxin-regulated root apical meristem patterning // Proceedings of the 7th International Conference on Bioinformatics of Genome Regulation and Structure (BGRS2010, 20-27 June, Novosibirsk, Russia), Novosibirsk, 2010.

2009:

V.V. Mironova, M.P. Ponomarenko, N.A. Omelyanchuk, V.A. Likhoshvai. AUXIN REGULATED ROOT PATTERNING: THE MATHEMATICAL MODEL AND KEY GENETIC MECHANISMS. German-Russian Forum Biotechnology. Novosibirsk June 2009.
V.V. Mironova, Omelyanchuk NA, Yosiphon G, Fadeev SI, Kolchanov NA, Mjolsness E, Likhoshvai VA. AUXIN REGULATED ROOT PATTERNING: THE MATHEMATICAL MODEL OF AUXIN TRANSPORT ALONG THE CENTRAL ROOT AXIS. Miniprogram “Morphodynamics in Plants, Animals and Beyond”. August-September 2009. Santa-Barbara, USA.
Mironova V.V., Omelyanchuk N.A., Likhoshvai V.A. Modeling of auxin distribution in root: rhizotaxis is defined by auxin regulation of its own transport. In proceedings of THE INTERNATIONAL MOSCOW CONFERENCE ON COMPUTATIONAL MOLECULAR BIOLOGY (MCCMB). Moscow. July 2009. p. 236-237.

2008:

Mironova V., Likhoshvai V., Omelyanchuk N.A., Mjolsness E., Kolchanov N.A. Acropetal auxin transport mediates root patterning in plants // In Proceeding of GARNet-SEB Symposium. 2008. Nottingham. England. P 17.
Mironova V.V., Omelyanchuk N.A., Fadeev S.I., Kogai V.V., Yosiphon G., Mjolsness E., Likhoshvai V.A. Auxin regulation of its own transport determines the root tip structure in plants. In Proceedings of the sixth international conference on Bioinformatics of Genome Regulation and Structure. 2008. p. 161.
Mironova V.V., Zalevsky E.M., Omelyanchuk N.A. PGNS-root – a database on expression of genes in plant root development. In Proceedings of the sixth international conference on Bioinformatics of Genome Regulation and Structure. 2008. p. 162.

Teaching:

2009-till present – Novosibirsk State University, Faculty of Natural Sciences. Author of original lectures focused on mathematical modeling of auxin transport, databasing in plant genetics and application of bioinformatics methods for plant genetics.

Grants:

RFBR 11-04-01254 “Combined experimental and computational approach for investigation of molecular-genetic mechanisms of auxin distribution in plant roots“,

RFBR 10-01-00717 “Symmetry and chaos in gene nets”,

SB RAS Interdisciplinary integration project №107 “The methods for differential-difference equations investigation and their applications to biological researches»,

SB RAS Interdisciplinary integration project №119 “Postgenome bioinformatics: computer analysis and modelling of molecular-genetic systems”,

NSF FIBR EF-0330786 “Development Modeling and Bioinformatics”.

NSF PHY05-51164 for participation to minisimposium “Morphodynamics in Plants, Animals and Beyond”. August-September 2009. KITP, Santa-Barbara, USA

Papers:

2011:

Denis Ponomaryov, Nadezhda Omelianchuk, Victoria Mironova, Evgeny Zalevsky, Nikolay Podkolodny, Eric Mjolsness, and Nikolay Kolchanov. From published expression and phenotype data to structured knowledge: The Arabidopsis gene net supplementary database and its applications // Lecture Notes in Artificial Intelligence. In print

2010:

Mironova VV, Omelyanchuk NA, Yosiphon Guy, Fadeev SI, Kolchanov NA, Mjolsness E., Likhoshvai VA How acropetal auxin flow determines cell fate specification along the central axis in root development. BMC Systems Biology. 2010, 4:98.
V.V. Mironova, N.A. Omelyanchuk, P.M. Ponomarenko, M.P. Ponomarenko, N.A. Kolchanov. SPECIFIC/NON-SPECIFIC BINDING OF TBP TO PROMOTER DNA OF THE AUXIN RESPONSE FACTOR GENES IN PLANTS CORRELATES WITH ARFs FUNCTION ON GENE TRANSCRIPTION (ACTIVATOR/REPRESSOR). Doklady Biochemistry and Biophysics. Vol. 433, pp. 191–196.

2009:

N. A. Omelyanchuk, V. V. Mironova, N. A. Kolchanov. Plant Developmental Genetics: Integrating Data from Different Experiments in Databases. Russian Journal of Genetics, 2009, Vol. 45, No. 11, pp. 1302–1316.
Likhoshvai V.A., Omelyanchuk N.A., Mironova V.V., Kazantsev F.V., Akberdin I.R., Korolev V.K., Fadeev S.I., Kolchanov N.A. Modeling of auxin regulated lateral organ initiation in Arabidopsis thaliana L. Informational Vestnik Vogis. 2009. Vol. 13. N 1. 176-185.

2008:

G. G. Lazareva, V. V. Mironova, N. A. Omelyanchuk, I. V. Shvab, V. A. Vshivkov, D. N. Gorpinchenko, S. V. Nikolaev and N. A. Kolchanov. Mathematical modeling of plant morphogenesis // Numerical Analysis and Applications. 2008. V. 1. № 2. P. 123-134

2007:

V. A. Likhoshvai, N. A. Omel’yanchuk, V. V. Mironova, S. I. Fadeev, E. D. Mjolsness and N. A. Kolchanov. Mathematical model of auxin distribution in the plant root. Russian Journal of Developmental Biology. 2007. V. 38, № 6. p. 446–456.
I. R. Akberdin., E. A. Ozonov., V.V. Mironova, N. A. Omelyanchuk., V. A. Likhoshvai., D. N. Gorpinchenko., N.A. Kolchanov. A cellular automaton to model the development of primary shoot meristems of Arabidopsis thaliana. Journal of Bioinformatics and Computational Biology. 2007. V. 5. N. 02B p. 641-650.

2006:

N. Omelyanchuk, V. Mironova, A. Poplavsky, N. Podkolodny, N. Kolchanov, E. Mjolsness, E. Meyerowitz (2006) AGNS-a database on expression of Arabidopsis genes. Bioinformatics of Genome Regulation and Structure II. Springer Science+Business Media, Inc. 433-442.
N. A. Omelyanchuk, V. V. Mironova, E. M. Zalevsky, I. S. Shamov, A. S. Poplavsky, N. L. Podkolodny, D. K. Ponomaryov, S. V. Nikolaev, E. D. Mjolsness, E. M. Meyerowitz, and N. A. Kolchanov A Systems Approach to Morphogenesis in Arabidopsis thaliana: I. AGNS Database // Biofizika, 2006 V.51, Suppl.1, p. 75-83.
S. V. Nikolaev, S. I. Fadeev, A. V. Penenko, V. V. Lavrekha, V. V. Mironova, N. A. Omelyanchuk, E. D. Mjolsness, and N. A. Kolchanov A Systems Approach to Morphogenesis in Arabidopsis thaliana: II. Modeling the Regulation of Shoot Apical Meristem Structure // Biofizika, 2006 V.51, Suppl.1, p. 83-90.
I. R. Akberdin, E. A. Ozonov, V. V. Mironova, D. N. Gorpinchenko, N. A. Omelyanchuk, V. A. Likhoshvai, and N. A. Kolchanov A Cellular Automaton Model of Morphogenesis in Arabidopsis thaliana // Biofizika, 2006 V.51, Suppl.1 p. 91-94

Biomodels Group

Mironova V